Bilayer Tablets of Atorvastatin Calcium and Nicotinic Acid: Formulation and Evaluation

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Bilayer tablets of atorvastatin calcium and nicotinic acid: formulation and evaluation.

The objective of the study is to formulate bilayer tablets consisting of atorvastatin calcium (AT) as an immediate release layer and nicotinic acid (NA) as an extended release layer. The immediate release layer was prepared using super disintegrant croscarmellose sodium and extended release layer using hydroxypropylmethyl cellulose (HPMC K100M). Both the matrix and bilayer tablets were evaluate...

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Formulation and Evaluation of Bilayer Floating Matrix Tablets For Captopril

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Formulation and Evaluation of Solid Dispersion of Atorvastatin Calcium

The present study was designed to improve the solubility and hence enhance the dissolution of hydrophobic drug Atorvastatin calcium (ATC) in order to increase its bioavailability. Solid dispersion of atorvastatin calcium using carrier PEG 4000 was formulated in different ratios by conventional fusion and microwave induced fusion method. In particular, the Microwave technology has been considere...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2008

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.56.1455